Gene set enrichment analysis and protein-protein interaction network analysis after sciatic nerve injury
نویسندگان
چکیده
منابع مشابه
protein-protein interaction network analysis of cirrhosis liver disease
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MOTIVATION Assessing functional associations between an experimentally derived gene or protein set of interest and a database of known gene/protein sets is a common task in the analysis of large-scale functional genomics data. For this purpose, a frequently used approach is to apply an over-representation-based enrichment analysis. However, this approach has four drawbacks: (i) it can only scor...
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BACKGROUND The aim of this study was to investigate the gene expression profile of thoracic propriospinal neurons between post-injury rat and controls. MATERIALS AND METHODS Microarray dataset GSE20907 was downloaded from GEO database, including 12 Spinal Cord Injury (SCI) rat and 12 controls. Student's t test was employed to identified differentially expressed genes with a fold-change > 1.2....
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ژورنال
عنوان ژورنال: Annals of Translational Medicine
سال: 2020
ISSN: 2305-5839,2305-5847
DOI: 10.21037/atm-20-4958